Carla Marzetti
Biography
Degree in Biological Sciences and registration as a Biologist, Director of the Valsambro Analysis Laboratory from 1980 to the present day, scientific consultant for pharmaceutical companies for the study and formulation of food supplements. Lecturer in CME courses. Through collaborations with universities and research centres, he has developed new diagnostic tests on intestinal microbiota and low-grade inflammation. He has deepened the technique in the Dark Field with new hyperspectral systems and nanotechnologies and collaborates with foreign laboratories on refined techniques such as ‘Elispot’ for the diagnostics of endocellular bacteria, viruses and parasites transmitted by hematophagous insects.
Abstract
The gut microbiota contributes to the digestion of food, synthesises essential vitamins and minerals for proper cell function. With its metabolites it is closely connected with the development and modulation of the immune system, it governs the intestinal mucosa and counteracts its permeability, it regulates the production of neurotransmitters as an actor in the gut-brain axis. The gut microbiota is capable of presiding over all these functions, provided it is in a state of equilibrium, termed eubiosis. Similarly, dysbiosis, which is at the root of low-intensity chronic inflammation of the intestinal mucosa, can be the trigger for major intestinal disorders, such as lBS, IBD, leaky gut, SIBO, etc. The study of both the bacterial and fungal microbiota will therefore be able to highlight the persistence of low pathogenic bacteria, the overgrowth of proinflammatory microorganism families and the deficiency of protective flora. Metabolomics will provide, through the examination of metabolites, the expression of the production of both necessary and toxic substances of bacteria and fungi even if they are hidden in the mucosa or organised in biofilms and therefore not present in the faecal sample This educational pathway will teach us how to read and interpret the examination of the microbiota and the sequence of related metabolites leading to the formulation of a functional and specific treatment.